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Explore videos featuring leading oncologists offering their expert insights on key topics related to TEVIMBRA, including clinical data from phase 3 trials, product design, dosing, and access.

Dosing Flexibility with TEVIMBRA

Ronan J. Kelly, MD, MBA, reviews dosing with TEVIMBRA, including its flexible regimen options across upper GI cancers.1

Navigating Formulary Access to TEVIMBRA

Dani Castillo, MD, discusses the process for obtaining formulary approval for TEVIMBRA in her practice.

Overall Survival Data and the National Comprehensive Cancer Network® (NCCN®) Recommendations

Marcia Cruz-Correa, MD, PhD, AGAF, FASGE discusses the latest NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) in
1L ESCC and 1L GC/GEJC and examines overall survival data for patients treated with tislelizumab-jsgr (TEVIMBRA®) + chemotherapy
vs placebo + chemotherapy.

PD-L1 Testing (TAP vs CPS)

Ronan J. Kelly, MD, MBA, explains TAP, the PD-L1 expression methodology used in the clinical trials of TEVIMBRA.

RATIONALE-305 OS Subgroup Analyses

Dani Castillo, MD, reviews subgroup analyses of overall survival, which included positive overall survival with TEVIMBRA + chemotherapy in patients with peritoneal metastases.<ss>2

RATIONALE-305 Study Design

Ronan J. Kelly, MD, MBA, reviews RATIONALE-305, a phase 3 trial that evaluated efficacy and safety outcomes with TEVIMBRA + chemotherapy in patients with 1L, unresectable or metastatic, HER2-negative GC or GEJC.

RATIONALE-306 Study Design

Marica Cruz-Correa, MD, PhD, AGAF, FASGE, reviews RATIONALE-306, a phase 3 trial that evaluated efficacy and safety outcomes with TEVIMBRA + chemotherapy in patients with 1L, unresectable, advanced or metastatic ESCC.

TEVIMBRA Mechanism of Action

Ronan J. Kelly, MD, MBA, discusses how TEVIMBRA is a unique PD-1 inhibitor.

1L, first line; ESCC, esophageal squamous cell carcinoma; GC, gastric cancer; GEJC, gastroesophageal junction cancer; GI, gastrointestinal; HER2, human epidermal growth factor receptor 2; PD-L1, programmed death ligand 1.

References: 1. TEVIMBRA. Prescribing Information. BeOne Medicines USA, Inc.; 2025. 2. Sonbol MB, Rha SY, Xu RH, et al. Abstract and poster presented at: ASCO Gastrointestinal Cancers Symposium; January 8-10, 2026. San Francisco, CA. Abstract 378, poster D9.

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